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HRID2069216

反应详情

EQUATION

反应方程式

HRID 2069216 的结构方程式

REACTANTS

反应物

2
结构：NCCCCc1ccccc1
HCID83242

4-Phenylbutylamine

C10H15N

结构：CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O
HCID58964482

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(NCCCCc3ccccc3)cc2c1=O
HCID11648022

未命名化合物

收率 19%

PROCEDURE

实验过程

N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (20 mg, 0.0628 mmol) is reacted with 4-phenyl-butylamine according to the GPA but purified, due to low solubility, by preparative TLC (eluent: hexane/ethyl acetate/acetic acid, 3/7/0.1) affording 5.4 mg (19%) of a red powder. Rt=5.93 min.

WORKUP

后处理

  1. custompurified, due to low solubility, by preparative TLC (eluent: hexane/ethyl acetate/acetic acid, 3/7/0.1)