2-Phenoxyethanamine → HCID 11553852, compound

HRID 2069219Notes

Reaction equation

HRID 2069219 reaction equation
F[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]2=[O:21].[O:22]([CH2:29][CH2:30][NH2:31])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[N+:12]([C:11]1[CH:10]=[C:9]2[C:4]([C:5](=[O:21])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:7](=[O:15])[NH:8]2)=[CH:3][C:2]=1[NH:31][CH2:30][CH2:29][O:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 156512-PhenoxyethanamineHCID 58964482N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide

Product 1

HCID 11553852HCID 11553852, compoundYield 52%

Procedure

N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (20 mg, 0.0628 mmol) is reacted with 2-phenoxy-ethylamine according to the GPA affording 14 mg (52%) of a red powder. Rt=5.25 min.

Sources & evidence

ORD record
ord-892c3f8aa4b1416bb7065e820bb651c5
Source dataset
uspto-grants-2012_10
Patent number
US08299085B2

Reaction notes

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