Isopropylamine → HCID 11595591, compound

HRID 2069227Notes

Reaction equation

HRID 2069227 reaction equation
F[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]2=[O:21].[CH:22]([NH2:25])([CH3:24])[CH3:23]>>[CH:22]([NH:25][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]2=[O:21])([CH3:24])[CH3:23]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 58964482N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide

Product 1

HCID 11595591HCID 11595591, compoundYield 58%

Procedure

N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (30 mg, 0.0943 mmol) is reacted with isopropylamine according to the GPA affording 19.6 mg (58%) of a red powder. Rt=4.44 min.

Sources & evidence

ORD record
ord-519090ede30e43ec8106b19d8f290a52
Source dataset
uspto-grants-2012_10
Patent number
US08299085B2

Reaction notes

Loading…