HCID 66933397, compound → HCID 66933298, compound

HRID 2069391Notes

Reaction equation

HRID 2069391 reaction equation
[CH3:1][NH:2][C:3]1[N:8]=[C:7]([C:9]([OH:11])=[O:10])[CH:6]=[C:5]([CH2:12][CH2:13][CH3:14])[N:4]=1.[CH2:15](C1N=C(S(C)(=O)=O)N=C(C(O)=O)C=1)C(C)C>>[CH2:12]([C:5]1[N:4]=[C:3]([NH:2][CH3:1])[N:8]=[C:7]([C:9]([OH:11])=[O:10])[CH:6]=1)[CH:13]([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 66933397HCID 66933397, compoundHCID 66933398HCID 66933398, compound

Product 1

HCID 66933298HCID 66933298, compound

Procedure

The title compound is obtained as a beige solid (84 mg) in analogy to 2-methylamino-6-propyl-pyrimidine-4-carboxylic acid starting from 6-isobutyl-2-methanesulfonyl-pyrimidine-4-carboxylic acid; LC-MS: tR=0.63 min, [M+H]+=209.99.

Sources & evidence

ORD record
ord-df809bd0b7d9408c9a801d55cff50d77
Source dataset
uspto-grants-2012_10
Patent number
US08299086B2

Reaction notes

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