Dimethylamine → HCID 66933782, compound

HRID 2069392Notes

Reaction equation

HRID 2069392 reaction equation
[CH3:1][NH:2][C:3]1N=C(C(O)=O)C=C(CCC)N=1.[CH2:15]([C:19]1[N:24]=[C:23](S(C)(=O)=O)[N:22]=[C:21]([C:29]([OH:31])=[O:30])[CH:20]=1)[CH:16]([CH3:18])[CH3:17].CNC>>[CH3:1][N:2]([CH3:3])[C:23]1[N:22]=[C:21]([C:29]([OH:31])=[O:30])[CH:20]=[C:19]([CH2:15][CH:16]([CH3:18])[CH3:17])[N:24]=1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 66933397HCID 66933397, compoundHCID 66933398HCID 66933398, compound

Product 1

HCID 66933782HCID 66933782, compound

Procedure

The title compound is obtained as a beige solid (132 mg) in analogy to 2-methylamino-6-propyl-pyrimidine-4-carboxylic acid starting from 6-isobutyl-2-methanesulfonyl-pyrimidine-4-carboxylic acid and 40% aq. dimethylamine; LC-MS: tR=0.78 min, [M+H]+=224.03.

Sources & evidence

ORD record
ord-f833c0c8922f40488f761629a6bf7d05
Source dataset
uspto-grants-2012_10
Patent number
US08299086B2

Reaction notes

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