Isopropylamine → HCID 66933429, compound

HRID 2069393Notes

Reaction equation

HRID 2069393 reaction equation
CNC1N=C(C(O)=O)[CH:6]=[C:5]([CH2:12]CC)[N:4]=1.[CH2:15]([C:19]1[N:24]=[C:23](S(C)(=O)=O)[N:22]=[C:21]([C:29]([OH:31])=[O:30])[CH:20]=1)[CH:16]([CH3:18])[CH3:17].C(N)(C)C>>[CH2:15]([C:19]1[N:24]=[C:23]([NH:4][CH:5]([CH3:12])[CH3:6])[N:22]=[C:21]([C:29]([OH:31])=[O:30])[CH:20]=1)[CH:16]([CH3:18])[CH3:17]

Participants

4

Reactant 3

HCID 6363IsopropylamineHCID 66933397HCID 66933397, compoundHCID 66933398HCID 66933398, compound

Product 1

HCID 66933429HCID 66933429, compound

Procedure

The title compound is obtained as a beige solid (103 mg) in analogy to 2-methylamino-6-propyl-pyrimidine-4-carboxylic acid starting from 6-isobutyl-2-methanesulfonyl-pyrimidine-4-carboxylic acid and isopropylamine; LC-MS: tR=0.77 min, [M+H]+=238.04.

Sources & evidence

ORD record
ord-136762296fcd4e35a7ef8e87b2213151
Source dataset
uspto-grants-2012_10
Patent number
US08299086B2

Reaction notes

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