Potassium tert-butoxide → HCID 66933517, compound

HRID 2069395Notes

Reaction equation

HRID 2069395 reaction equation
[CH2:1]([O:3][C:4]1[N:9]=[C:8]([C:10]([OH:12])=[O:11])[CH:7]=[C:6]([CH2:13][CH3:14])[N:5]=1)C.[CH2:15](OC(C1C=C(CCC)N=C(S(C)(=O)=O)N=1)=O)C.CC([O-])(C)C.[K+]>CO>[CH3:1][O:3][C:4]1[N:9]=[C:8]([C:10]([OH:12])=[O:11])[CH:7]=[C:6]([CH2:13][CH2:14][CH3:15])[N:5]=1

Participants

5

Reactant 3

HCID 23665647Potassium tert-butoxideHCID 66933435HCID 66933435, compoundHCID 66933444HCID 66933444, compound

Product 1

HCID 66933517HCID 66933517, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound is obtained as a beige solid (84 mg) in analogy to 2-ethoxy-6-ethyl-pyrimidine-4-carboxylic acid starting from 2-methanesulfonyl-6-propyl-pyrimidine-4-carboxylic acid ethyl ester, KOtBu and methanol; LC-MS: tR=0.71 min, [M+H]+=196.96.

Sources & evidence

ORD record
ord-171a40212904484a9f37d7b648e859a1
Source dataset
uspto-grants-2012_10
Patent number
US08299086B2

Reaction notes

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