HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-6-methylphenol → 4-Hydroxy-3-methoxy-5-methylbenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-6-methylphenol | HCID 76173 | — |
| Reactant | 3-Ethyl-4-hydroxy-5-methylbenzonitrile | HCID 59759950 | — |
| Product | 4-Hydroxy-3-methoxy-5-methylbenzonitrile | HCID 19038318 | — |
Reaction Steps
The title compound is prepared from commercially available 2-hydroxy-3-methoxy-toluene in analogy to literature procedures (see 3-ethyl-4-hydroxy-5-methyl-benzonitrile); LC-MS: tR=0.84 min. 1H NMR (CDCl3): δ 2.27 (s, 3H), 3.93 (s, 3H), 6.24 (s, 1H), 6.97 (d, J=1.3 Hz, 1H), 7.12 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299086B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-a6ea6eb9dc764daab7c13daa92b14d7a |
| Source note | uspto-grants-2012_10 |