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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2069452Generated: November 1, 2026

(-)-Epichlorohydrin → HCID 87477527, compound

https://huagongshe.com/reaction/2069452

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(-)-EpichlorohydrinHCID 2734062—
ReactantHCID 136339866HCID 136339866—
ReactantHCID 136339911HCID 136339911—
ProductHCID 87477527HCID 87477527—

Reaction Steps

2-Ethyl-4-[3-(2-isopropylamino-6-methyl-pyrimidin-4-yl)-[1,2,4]oxadiazol-5-yl]-6-methyl-phenol is reacted with R-epichlorohydrine in analogy to Intermediate 1 to give (S)-{4-[5-(3-ethyl-5-methyl-4-oxiranyl methoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methyl-pyrimidin-2-yl}-iso-propyl-amine as a yellow oil; LC-MS: tR=1.10 min; [M+H]+=410.55.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08299086B2
Source datasetuspto-grants-2012_10
ORD IDord-844afac5aeaf489f8b755032215aa58a
Source noteuspto-grants-2012_10