HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid → N-(2-Hydroxymethyl-3-methyl-3H-imidazo[4,5-b]pyrid-6-yl)-5-fluoro-1-[(3-fluoro-phenyl)methyl]-1H-indole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid | HCID 57431513 | — |
| Reactant | (6-Amino-3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)methanol | HCID 66888727 | — |
| Product | N-(2-Hydroxymethyl-3-methyl-3H-imidazo[4,5-b]pyrid-6-yl)-5-fluoro-1-[(3-fluoro-phenyl)methyl]-1H-indole-2-carboxamide | HCID 66889444 | — |
Reaction Steps
Compound 6 is synthesized according to a process similar to that described in Example 1.2, starting with 6-amino-2-hydroxymethyl-3-methyl-3H-imidazo[4,5-b]-pyridine described in the preceding step and 5-fluoro-1-[(3-fluorophenyl)methyl]-1H-indole-2-carboxylic acid described in step 1.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299114B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-ee837f16a93846de8ab17e13cefb775e |
| Source note | uspto-grants-2012_10 |