HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2069837Generated: October 31, 2026
Dimethylformamide dimethyl acetal → HCID 178428505, compound
https://huagongshe.com/reaction/2069837
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | HCID 59473790 | HCID 59473790 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178428505 | HCID 178428505 | — |
Reaction Steps
A suspension of 4-Dimethylamino-2-fluoro-6-methyl-benzamide (0.696 g, 3.55 mmol) with dimethylformamide-dimethylacetal (0.551 mL, 3.90 mmol) in THF (3 mL) was heated to 60° C. After 14 h., solvent was removed to give 4-Dimethylamino-N-[1-dimethylamino-meth-(E)-ylidene]-2-fluoro-6-methyl-benzamide as an oil, which eventually crashed out as a white solid (0.890 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08299077B2 |
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| Source dataset | uspto-grants-2012_10 |
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| ORD ID | ord-403dba85e296405ea804f5844ada491f |
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| Source note | uspto-grants-2012_10 |
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