反应详情

温度

120 °C

A thick-walled microwave bottle equipped with a stirbar was charged with 3-chloroquinoxalin-2-amine (1.0 equiv) and 20 volume equivalents of 3-aminopentane. The bottle was fitted with a septum and cap and heated to 120° C. in a microwave for 30 min. The resulting solution was concentrated in vacuo. Flash chromatography (20%-60% EtOAc/Hexanes) provided the title compound (78%) as a yellow solid. LCMS m/z (APCI)=231.1 (M+H).

1. customA thick-walled microwave bottle equipped with a stirbar
2. customThe bottle was fitted with a septum
3. customcap
4. concentrationThe resulting solution was concentrated in vacuo