HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyridine → N-(5-bromopyridin-2-yl)-N'-(2-fluoro-5-methylphenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Reactant | 3-Fluorophenyl isocyanate | HCID 123064 | — |
| Reactant | 2-Fluoro-5-methylphenyl isocyanate | HCID 2733377 | — |
| Product | N-(5-bromopyridin-2-yl)-N'-(2-fluoro-5-methylphenyl)urea | HCID 66680783 | — |
Reaction Steps
The desired product was prepared by substituting 2-amino-5-bromopyridine and 1-fluoro-2-isocyanato-4-methylbenzene for Example 15G and 1-fluoro-3-isocyanatobenzene, respectively, in Example 15H. MS (ESI(+)) m/e 324.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299243B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-922aa197267d46369e615d8bf0aca8ac |
| Source note | uspto-grants-2012_10 |