HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitro-4-(4-(3-pyridyl)pyrimidin-2-yloxy)phenylamine → 4-(4-(3-Pyridyl)pyrimidin-2-yloxy)benzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitro-4-(4-(3-pyridyl)pyrimidin-2-yloxy)phenylamine | HCID 22041340 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(4-(3-Pyridyl)pyrimidin-2-yloxy)benzene-1,2-diamine | HCID 22041328 | — |
Reaction Steps
The mixture containing 2-nitro-4-(4-(3-pyridyl)pyrimidin-2-yloxy)phenylamine in methanol with catalytic amount of 10% Pd/C was hydrogenated until disappearance of yellow color to yield 4-(4-(3-pyridyl)pyrimidin-2-yloxy)benzene-1,2-diamine. MS: MH+=279.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299108B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-26b330eb636044dfbfe45dc4e94c6c54 |
| Source note | uspto-grants-2012_10 |