[(4-Nitrophenyl)ethyl]benzylamine → [(4-Aminophenyl)ethyl]benzylamine

HRID 2070285Notes

Reaction equation

HRID 2070285 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][NH:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:6][CH:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH2:11][NH:12][CH2:13][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 10999672[(4-Nitrophenyl)ethyl]benzylamine

Product 1

HCID 54424736[(4-Aminophenyl)ethyl]benzylamine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The mixture containing [(4-nitrophenyl) ethyl]benzylamine in methanol with catalytic amount of 10% Pd/C was hydrogenated until disappearance of yellow color to yield [(4-aminophenyl)ethyl]benzylamine. MS: MH+=226.

Sources & evidence

ORD record
ord-29e8bb7e33d74dbdb76bc1c8e5c931d4
Source dataset
uspto-grants-2012_10
Patent number
US08299108B2

Reaction notes

Loading…