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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2070302Generated: November 1, 2026

{4-[2-Methoxy-4-(methylamino)-5-nitrophenoxy] (2-pyridyl)}-n-methylcarboxamide → {4-[3-Amino-6-methoxy-4-(methylamino)phenoxy](2-pyridyl)}-n-methylcarboxamide

https://huagongshe.com/reaction/2070302

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{4-[2-Methoxy-4-(methylamino)-5-nitrophenoxy] (2-pyridyl)}-n-methylcarboxamideHCID 131725843—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product{4-[3-Amino-6-methoxy-4-(methylamino)phenoxy](2-pyridyl)}-n-methylcarboxamideHCID 58385465—

Reaction Steps

A solution of {4-[2-methoxy-4-(methylamino)-5-nitrophenoxy](2-pyridyl)}-N-methylcarboxamide. In methanol was hydrogenated with 10% Pd/C. The catalyst was filtered off and the solvent was concentrated to yield {4-[3-amino-6-methoxy-4-(methylamino)phenoxy](2-pyridyl)}-N-methylcarboxamide. MS:MH+: 302.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08299108B2
Source datasetuspto-grants-2012_10
ORD IDord-9dd67b1f5b1f4448b4bddd53fd6e7d48
Source noteuspto-grants-2012_10