2-Fluoro-3-(4-methyl-piperazin-1-yl)-6-nitro-phenylamine → HCID 22040478, compound

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Reaction Steps

A sealed tube was charged with suspension of 1 (270 mg, 0.9 mmol) and Lindlar catalyst (192 mg, 10 mol %) in methanol (5 mL) then placed on a Parr shaker. Reaction purged with H2 at 60 psi for 1 h. Solids filtered through Celite and washed with methanol, then concentrated to give 2 as a brown semi-solid. LCMS m/z 273.3 (MH+), Rt 1.56 min.

Provenance & Evidence