HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-methyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate → [2-methyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-methyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate | HCID 53237932 | — |
| Reactant | Diisobutylaluminumhydride toluene | HCID 86583787 | — |
| Product | [2-methyl-1-(phenylsulfonyl)-1H-pyrrol-3-yl]methanol | HCID 66924976 | — |
Reaction Steps
By a similar operation as in Reference Example 13 and using ethyl 2-methyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate (8.05 g) and 1.5 mol/L diisobutylaluminum hydride toluene solution (55 mL), the title compound was obtained as white crystals (yield 6.61 g, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299261B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-22033125c77f45b2aa0f396c19b3d180 |
| Source note | uspto-grants-2012_10 |