HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-(Benzyloxy)phenyl)propan-2-amine → Methyl 3-[3-({1-[2-(benzyloxy)phenyl]-1-methylethyl}amino)-5-bromo-2-oxopyrazin-1(2H)-yl]-4-ethylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-(Benzyloxy)phenyl)propan-2-amine | HCID 66688850 | — |
| Reactant | methyl 3-(3,5-dibromo-2-oxopyrazin-1(2H)-yl)-4-ethylbenzoate | HCID 66689256 | — |
| Product | Methyl 3-[3-({1-[2-(benzyloxy)phenyl]-1-methylethyl}amino)-5-bromo-2-oxopyrazin-1(2H)-yl]-4-ethylbenzoate | HCID 66688684 | — |
Reaction Steps
The subtitle compound was prepared from methyl 3-(3,5-dibromo-2-oxopyrazin-1(2H)-yl)-4-ethylbenzoate (Example 288b) and α,α-dimethyl-2-(phenylmethoxy)-benzenemethanamine (Example 198d) using a similar method to that described for Example 252h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299246B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-aee459915f7c41f3b28ea11652ff43ee |
| Source note | uspto-grants-2012_10 |