4-Bromo-2-fluorobenzaldehyde → HCID 86761642, compound

HRID 2070891Notes

Reaction equation

HRID 2070891 reaction equation
[C:1]1([C:7]2[N:12]3[N:13]=[C:14]([NH:16][C:17]4[CH:25]=[CH:24][C:20]5[CH:21]=N[O:23][C:19]=5[CH:18]=4)[N:15]=[C:11]3[CH:10]=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C2N3N=C(N)N=C3C=CC=2)C=CC=CC=1.BrC1C=CC(C=O)=C([F:51])C=1.C1(NC2N=C3C=CC=C(C4C=CC=CC=4)N3N=2)C=CC=CC=1>>[F:51][C:21]1[CH:18]=[C:17]([NH:16][C:14]2[N:15]=[C:11]3[CH:10]=[CH:9][CH:8]=[C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[N:12]3[N:13]=2)[CH:25]=[CH:24][C:20]=1[CH:19]=[O:23]

Participants

5

Reactant 4

HCID 1435174-Bromo-2-fluorobenzaldehydeHCID 59276436HCID 59276436, compoundHCID 59276511HCID 59276511, compoundHCID 672931715-Phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Product 1

HCID 86761642HCID 86761642, compound

Procedure

N-(5-Phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzo[d]isoxazol-6-amine. 2-Fluoro-4-(5-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamino)benzaldehyde was prepared from 5-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine and 4-bromo-2-fluoro-benzaldehyde following the procedure described for the synthesis of N,5-diphenyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine.

Sources & evidence

ORD record
ord-0d1c4f7905764863bc625cbbf5e00572
Source dataset
uspto-grants-2012_10
Patent number
US08299056B2

Reaction notes

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