4-Isopropylpyridine → 2-Fluoro-5-(1-methylethyl)pyridine

HRID 2070930Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:10])=[CH2:9])=[CH:4][N:3]=1.C(C1C=CN=CC=1)(C)C>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:10])[CH3:9])=[CH:4][N:3]=1

Participants

Reactant 2

HCID 696744-Isopropylpyridine

HCID 666003332-Fluoro-5-(1-methylethenyl)pyridine

Product 1

HCID 205879682-Fluoro-5-(1-methylethyl)pyridine

Procedure

2-fluoro-5-isopropylpyridine was synthesized from 2-fluoro-5-(prop-1-en-2-yl)pyridine following the general procedure as described for 4-isopropylpyridine.

Sources & evidence

ORD record: ord-1f46666748a34790bb9d83288b296b6a
Source dataset: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08299267B2

Reaction notes

Loading…