3-Cyano-5-isopentylpyridine → Benzyl 3-(aminomethyl)-5-bromophenylcarbamate

HRID 2070937Notes

Reaction equation

HRID 2070937 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:20])[O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:5]=[C:6]([C:8]#[N:9])[CH:7]=1.C(C1C=NC=C(CCC(C)C)C=1)#N>>[NH2:9][CH2:8][C:6]1[CH:5]=[C:4]([NH:10][C:11](=[O:20])[O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:3]=[C:2]([Br:1])[CH:7]=1

Participants

3

Reactant 2

HCID 686702083-Cyano-5-isopentylpyridineHCID 68671401benzyl N-(3-bromo-5-cyanophenyl)carbamate

Product 1

HCID 68669766Benzyl 3-(aminomethyl)-5-bromophenylcarbamate

Procedure

Benzyl 3-(aminomethyl)-5-bromophenylcarbamate was synthesized from benzyl 3-bromo-5-cyanophenylcarbamate following the general procedure as described for the 3-cyano-5-isopentylpyridine.

Sources & evidence

ORD record
ord-560777c560954d948156701c52794055
Source dataset
uspto-grants-2012_10
Patent number
US08299267B2

Reaction notes

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