3-(Dimethylamino)-5-(prop-1-en-2-yl)benzonitrile → 3-(aminomethyl)-5-isopropyl-N,N-dimethylaniline
Reaction equation
[CH3:1][N:2]([CH3:14])[C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([C:11]([CH3:13])=[CH2:12])[CH:10]=1)[C:6]#[N:7].C(C1C=NC=C(CCC(C)C)C=1)#N>>[NH2:7][CH2:6][C:5]1[CH:4]=[C:3]([CH:10]=[C:9]([CH:11]([CH3:13])[CH3:12])[CH:8]=1)[N:2]([CH3:14])[CH3:1]Participants
3
Procedure
3-(aminomethyl)-5-isopropyl-N,N-dimethylaniline was synthesized from 3-(dimethylamino)-5-(prop-1-en-2-yl)benzonitrile following the general procedure as described for the 3-cyano-5-isopentylpyridine.
Sources & evidence
- ORD record
- ord-3ff11e8652d94e8ba89159a634217d85
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08299267B2
Reaction notes
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