HCID 86647413, compound → HCID 68669579, compound

HRID 2070946Notes

Reaction equation

HRID 2070946 reaction equation
[N:1]([CH2:4][C:5]1[C:6]([CH3:15])=[N:7][C:8]([CH3:14])=[C:9]([C:11]([CH3:13])=[CH2:12])[CH:10]=1)=[N+]=[N-]>CO.[Pd]>[CH3:15][C:6]1[C:5]([CH2:4][NH2:1])=[CH:10][C:9]([C:11]([CH3:13])=[CH2:12])=[C:8]([CH3:14])[N:7]=1

Participants

4

Reactant 1

HCID 86647413HCID 86647413, compound

Product 1

HCID 68669579HCID 68669579, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of crude 3-(azidomethyl)-2,6-dimethyl-5-(prop-1-en-2-yl)pyridine and 10.2 mg of 10% Pd/C in 6 mL of MeOH was stirred at r.t. under H2 balloon. After 3 h the mixture was filtered through Celite and concentrated to provide (2,6-dimethyl-5-(prop-1-en-2-yl)pyridin-3-yl)methanamine.

Workup

  1. filtrationAfter 3 h the mixture was filtered through Celite
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-0caefa482a19495ea1d44cb15616ccc7
Source dataset
uspto-grants-2012_10
Patent number
US08299267B2

Reaction notes

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