3-Cyano-5-isopentylpyridine → (6-Methyl-5-(methylsulfonylmethyl)pyridin-2-yl)methanamine
Reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][C:3]=1[CH2:10][S:11]([CH3:14])(=[O:13])=[O:12].C(C1C=NC=C(CCC(C)C)C=1)#N>>[CH3:1][C:2]1[N:7]=[C:6]([CH2:8][NH2:9])[CH:5]=[CH:4][C:3]=1[CH2:10][S:11]([CH3:14])(=[O:13])=[O:12]Participants
3
Procedure
(6-methyl-5-(methylsulfonylmethyl)pyridin-2-yl)methanamine was synthesized from 6-methyl-5-(methylsulfonylmethyl)picolinonitrile following the general procedure as described above for the 3-cyano-5-isopentylpyridine.
Sources & evidence
- ORD record
- ord-db32a5892bd748b9b9d2e8b5710c4f51
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08299267B2
Reaction notes
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