N-(3-cyano-5-(prop-1-en-2-yl)phenyl)methanesulfonamide → N-(3-(aminomethyl)-5-isopropylphenyl)methanesulfonamide
Reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[CH:6]=[C:7]([C:9]([CH3:11])=[CH2:10])[CH:8]=1)#[N:2].C(C1C=NC=C(CCC(C)C)C=1)#N>>[NH2:2][CH2:1][C:3]1[CH:4]=[C:5]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])[CH:6]=[C:7]([CH:9]([CH3:11])[CH3:10])[CH:8]=1Participants
3
Procedure
N-(3-(aminomethyl)-5-isopropylphenyl)methanesulfonamide was synthesized from N-(3-cyano-5-(prop-1-en-2-yl)phenyl)methanesulfonamide following the general procedure as described above for the 3-cyano-5-isopentylpyridine.
Sources & evidence
- ORD record
- ord-fee4ab8bb262498c8cc044f2a21ca932
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08299267B2
Reaction notes
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