ethyl 1-tert-butyl-5-methyl-1H-pyrazole-4-carboxylate → HCID 59569900, compound

HRID 2070962Notes

Reaction equation

HRID 2070962 reaction equation
[N:1]([CH2:4][C:5]1[CH:6]=[N:7][N:8]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:9]=1[CH3:10])=[N+]=[N-].C(N1C(C)=C(C(OCC)=O)C=N1)(C)(C)C>>[C:11]([N:8]1[C:9]([CH3:10])=[C:5]([CH2:4][NH2:1])[CH:6]=[N:7]1)([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 13654177ethyl 1-tert-butyl-5-methyl-1H-pyrazole-4-carboxylateHCID 86647415HCID 86647415, compound

Product 1

HCID 59569900HCID 59569900, compound

Procedure

4-(azidomethyl)-1-tert-butyl-5-methyl-1H-pyrazole was generated from ethyl 1-tert-butyl-5-methyl-1H-pyrazole-4-carboxylate according to a procedure similar to that described for the 2,6 dimethyl 3,5-pyridyl derivative, then reduced to the crude primary amine, following procedures described herein.

Sources & evidence

ORD record
ord-b46bc853faa6455a8f113a899461a030
Source dataset
uspto-grants-2012_10
Patent number
US08299267B2

Reaction notes

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