HCID 68670765, compound → HCID 59569780, compound

HRID 2070964Notes

Reaction equation

HRID 2070964 reaction equation
[N:1]([CH2:4][C:5]1[CH:6]=[N:7][N:8]([CH2:11][CH2:12][O:13][CH3:14])[C:9]=1[CH3:10])=[N+]=[N-].COCCN1C(C)=C(C(OCC)=O)C=N1>>[CH3:14][O:13][CH2:12][CH2:11][N:8]1[C:9]([CH3:10])=[C:5]([CH2:4][NH2:1])[CH:6]=[N:7]1

Participants

3

Reactant 2

HCID 68670765HCID 68670765, compoundHCID 86647416HCID 86647416, compound

Product 1

HCID 59569780HCID 59569780, compound

Procedure

4-(azidomethyl)-1-(2-methoxyethyl)-5-methyl-1H-pyrazole was generated from ethyl 1-(2-methoxyethyl)-5-methyl-1H-pyrazole-4-carboxylate according to a procedure similar to that described for the 2,6 dimethyl 3,5-pyridyl derivative, then reduced to the crude primary amine, following procedures described herein.

Sources & evidence

ORD record
ord-f2ad907704df486fbe2b5125c613157a
Source dataset
uspto-grants-2012_10
Patent number
US08299267B2

Reaction notes

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