2-Fluoro-6-methoxybenzaldehyde → 1-(2-Fluoro-6-methoxyphenyl)methanamine
Reaction equation
[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[C:3]=1[CH:4]=O.[NH2:12]CC1C=CC=C(C(C)(C)C)C=1O>>[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[C:3]=1[CH2:4][NH2:12]Participants
3
Procedure
(2-fluoro-6-methoxyphenyl)methanamine was synthesized from 2-fluoro-6-methoxybenzaldehyde using a similar procedure to the described synthesis of 2-(aminomethyl)-6-tert-butylphenol.
Sources & evidence
- ORD record
- ord-29cd50c4d284478ab9cf12cfe8d43a10
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08299267B2
Reaction notes
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