HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-(benzyl(methyl)amino)benzylcarbamate → Tert-butyl 3-(methylamino)benzylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-(benzyl(methyl)amino)benzylcarbamate | HCID 68670737 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Tert-butyl 3-(methylamino)benzylcarbamate | HCID 57763264 | — |
Reaction Steps
20% Pd(OH)2 0.076 g) was added to a stirred suspension of tert-butyl 3-(benzyl(methyl)amino)benzylcarbamate (0.248 g, 0.76 mmol, 1 eq) in 10 ml EtOH. A H2 balloon was added. After stirring overnight the mixture was filtered through Celite. The filter cake was rinsed with EtOAc (×3). The organics were combined and the solvent was removed in vacuo to yield tert-butyl 3-(methylamino)benzylcarbamate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299267B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-148f23d4ee9644468480518b4aae477d |
| Source note | uspto-grants-2012_10 |