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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2071070Generated: October 31, 2026

Tert-butyl benzofuran-2-ylmethylcarbamate → 5-Aminomethyl-3-isopropylisoxazole

https://huagongshe.com/reaction/2071070

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl benzofuran-2-ylmethylcarbamateHCID 68671575—
Reactant5-(Azidomethyl)-3-isopropylisoxazoleHCID 91104999—
Product5-Aminomethyl-3-isopropylisoxazoleHCID 6483898—

Reaction Steps

(3-isopropylisoxazol-5-yl)methanamine was synthesized from 5-(azidomethyl)-3-isopropylisoxazole following the general procedure as described herein including the protection-deprotection steps to improve the purity of the amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08299267B2
Source datasetuspto-grants-2012_10
ORD IDord-4be9d7cba96e4d2f9851eeb159db773e
Source noteuspto-grants-2012_10