HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R)-1-[(tert-butoxy)carbonyl]piperidine-2-carboxylic acid → HCID 52344966, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R)-1-[(tert-butoxy)carbonyl]piperidine-2-carboxylic acid | HCID 688618 | — |
| Reactant | HCID 42078478 | HCID 42078478 | — |
| Product | HCID 52344966 | HCID 52344966 | — |
| Product | HCID 68671640 | HCID 68671640 | — |
Reaction Steps
(R)-4-methyl-2-(piperidin-2-yl)thiazole was prepared following the same procedure as in the preparation of (R)-4-methyl-2-(pyrrolidin-2-yl)thiazole starting from the commercially available (R)-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid (Aldrich) to obtain (R)-tert-butyl 2-(4-methylthiazol-2-yl)piperidine-1-carboxylate which was deprotected using standard TFA conditions to obtain the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299267B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-62a604db2cf84bd693138c0ad529a812 |
| Source note | uspto-grants-2012_10 |