2-Fluoro-5-methylbenzoic acid → 4-Fluorobenzene-1,3-dicarboxylic acid
Reaction equation
[F:1]C1C=CC(C)=CC=1C(O)=O.F[C:13]1[CH:14]=[C:15]([C:22]([OH:24])=[O:23])[CH:16]=[C:17]([CH:21]=1)[C:18]([OH:20])=[O:19]>>[F:1][C:14]1[CH:13]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][C:15]=1[C:22]([OH:24])=[O:23]Participants
3
Procedure
4-fluoro-isophthalic acid was synthesized from 2-fluoro-5-methylbenzoic acid following the procedure described for 5-fluoro-isophthalic acid.
Sources & evidence
- ORD record
- ord-6dd6666ea59042e68caf1f930456d43a
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08299267B2
Reaction notes
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