HCID 59570870, compound → HCID 86647440, compound

HRID 2071169Notes

Reaction equation

HRID 2071169 reaction equation
ClC1C=C(C=C(C=O)N=1)C(OC)=O.[F:14][C:15]1[N:20]=[CH:19][C:18]([C:21]2[CH:26]=[C:25]([C:27]([O:29][CH3:30])=[O:28])[CH:24]=[C:23]([C:31](O)=[O:32])[N:22]=2)=[CH:17][CH:16]=1>>[F:14][C:15]1[N:20]=[CH:19][C:18]([C:21]2[CH:26]=[C:25]([C:27]([O:29][CH3:30])=[O:28])[CH:24]=[C:23]([CH:31]=[O:32])[N:22]=2)=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 59570870HCID 59570870, compoundHCID 722138911006598-63-5

Product 1

HCID 86647440HCID 86647440, compound

Procedure

methyl 6′-fluoro-6-formyl-2,3′-bipyridine-4-carboxylate was synthesized from methyl 2-chloro-6-formylisonicotinate and converted to 6′-fluoro-4-(methoxycarbonyl)-2,3′-bipyridine-6-carboxylic acid following the general procedures as described herein.

Sources & evidence

ORD record
ord-a458c9e3aab54eeebe3a5511194cfa9b
Source dataset
uspto-grants-2012_10
Patent number
US08299267B2

Reaction notes

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