Chloroacetaldehyde → HCID 21412834, compound

Participants

Reaction Conditions

Reaction Steps

2-Methyl-5-cyanoaniline (0.3 mole), the dimethyl acetal of 2-chloroacetaldehyde (0.3 mole) and sodium carbonate (20 grams) are charged into a glass reaction flask equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated to about 150° C. for a period of about 8 hours. After this time the mixture is filtered and the filtrate is distilled to yield the desired product the dimethyl acetal of 2-(2-methyl-5-cyanoanilino)acetaldehyde.

Provenance & Evidence