Methyl iodide → HCID 21413301, compound

Participants

Reaction Steps

A mixture of methyl 8-chloro-4,10-dihydro-4,10dioxo-1H-1-benzopyrano-[3,2-b]pyridine-2-carboxylate (7.0 g, 0.023 mole), methyl iodide (14 g, 0.099 mole) and potassium carbonate (3.22 g, 0.023 mole) in dimethyl formamide (100 ml) was stirred at 100° under nitrogen for 3 hrs. The reaction mixture was cooled. The product, which precipitated, was filtered, washed with water and dried. Recrystallization from DMF gave white crystals (6.3 g, 86%), m.p. 276°-278°.

Provenance & Evidence