HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Pyridin-4-ylacetamide → 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-acetamidopyridinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Pyridin-4-ylacetamide | HCID 21288 | — |
| Reactant | 4-(2-Iodoethyl)-1,2-dimethoxybenzene | HCID 597022 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-acetamidopyridinium iodide | HCID 21413259 | 67.7% |
Reaction Steps
1-(2-Iodoethyl)-3,4-dimethoxybenzene (29.3 g.) and 4-acetamidopyridine (14.0 g.) in absolute ethanol (100 ml.) were refluxed for 2.5 hours. The resulting crystalline material was collected and recrystallised from ethanol to give the title compound (29.1 g.)., m.p. 201°-202° C. (Found: C, 47.9; H, 4.9; N, 6.3; C17H21IN2O3 requires C, 47.7; H, 4.9; N, 6.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046767 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-969bfcdd2996412d939878d4e01c8a55 |
| Source note | uspto-grants-1977_09 |