HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Chloroethyl)-1,2,3-trimethoxybenzene → 1-[2-(3,4,5-Trimethoxyphenyl)ethyl]-4-benzamidopiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Chloroethyl)-1,2,3-trimethoxybenzene | HCID 13863331 | — |
| Reactant | 1-[2-(Cyclohexyl)ethyl]-4-benzamidopiperidine | HCID 21413269 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-[2-(3,4,5-Trimethoxyphenyl)ethyl]-4-benzamidopiperidine | HCID 21413258 | — |
Reaction Steps
Prepared in exactly the same way as for the compound of Example 1 except that 3,4,5-trimethoxyphenethyl chloride was used in place of cyclohexylethyl bromide. The title compound was obtained as a monohydrate (1.2 g.), m.p. 193°-4° C. (Found: C, 66.7; H, 7.6; N, 6.9. C20H30N2O4. H2O requires C, 66.4; H, 7.5; N, 6.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046767 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-b023d4e791964d5090a546cc15ce7527 |
| Source note | uspto-grants-1977_09 |