Water → HCID 21413419, compound

Participants

Reaction Steps

A solution of 15.3 g. (0.1 mol.) of 4-chlorophenyl-isocyanate in 120 ml. of toluene is added dropwise to the stirred solution of 8.61 g. (0.105 mol.) of 2-methyl-imidazole in 60 ml. of water at 10° to 12° C., under cooling. The reaction mixture is stirred at room temperature for one hour. The separated product is filtered off, washed with water and dried. 17.4 g. (74%) of 1-(4-chlorophenyl)-carbamoyl-2-methylimidazole are obtained; m.p.: 138°-140° C.

Provenance & Evidence