HCID 21413935, compound → HCID 21413934, compound

Participants

Reaction Steps

72 gm (0.15 mol) of the product obtained in step (a) were hydrogenated in 1.44 liters of methanol and in the presence of 5 gm of 5% palladium charcoal at 5 atmospheres and 60° C. After the absorption of hydrogen had ceased, the catalyst was filtered off, and the methanol was distilled out of the filtrate. The crystalline residue was stirred with acetonitrile, the mixture was vacuum-filtered, and the filter cake was recrystallized from ethanol, yielding 69 gm (95.% of theory) of the compound of the formula ##STR5## which had a melting point of 113° C.

Provenance & Evidence