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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2071472Generated: October 26, 2026

2-Aminophenol → 3'-Chloro-2'-hydroxy-p-toluanilide

https://huagongshe.com/reaction/2071472

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminophenolHCID 5801—
Reactant4-ChlorotolueneHCID 7810—
Reactant2-Amino-4,6-dichlorophenolHCID 10699—
Reactant2-Amino-6-chlorophenolHCID 6486025—
Product3'-Chloro-2'-hydroxy-p-toluanilideHCID 21413806—
Product3',5'-Dichloro-2'-hydroxy-p-toluanilideHCID 21413857—

Reaction Steps

When 2-amino-6-chlorophenol and 2-amino-4,6-dichlorophenol are used in place of o-aminophenol and when p-toluyl chloride is used in place of 3-fluoro-p-toluyl chloride in the above example, there is obtained 3'-chloro-2'-hydroxy-p-toluanilide and 3',5'-dichloro-2'-hydroxy-p-toluanilide, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04046905
Source datasetuspto-grants-1977_09
ORD IDord-0f4d7aa8535049d6ade96b9f0aa1b7f0
Source noteuspto-grants-1977_09