HRID2071475

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21413805

未命名化合物

PRODUCTS

生成物

HCID21413851

未命名化合物

HCID21413858

未命名化合物

HCID131710117

未命名化合物

PROCEDURE

实验过程

When 7-chloro-2-(4-bromomethylphenyl)benzoxazole, 5,7-dichloro-2-(4-bromomethylphenyl)benzoxazole and 4-(benzoxazol-2-yl)-1-bromobenzocyclobutene are used in place of 2-(4-bromomethyl-3-fluorophenyl)benzoxazole in the above example, there is obtained 4-(7-chlorobenzoxazol-2-yl)-phenylacetonitrile, 4-(5,7-dichlorobenzoxazol-2-yl)phenylacetonitrile, and 4-(benzoxazol-2-yl)-1-cyanobenzocyclobutene, respectively.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-54260708d3aa49b498640682edba388e
来源数据集: uspto-grants-1977_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04046905
来源说明: uspto-grants-1977_09

反应 SMILES

[Cl:1][C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([CH2:17]Br)=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[Cl:19][C:20]1[CH:21]=[C:22]([Cl:37])[C:23]2[O:27][C:26]([C:28]3[CH:33]=[CH:32][C:31]([CH2:34]Br)=[CH:30][CH:29]=3)=[N:25][C:24]=2[CH:36]=1.[O:38]1[C:42]2[CH:43]=[CH:44][CH:45]=[CH:46][C:41]=2[N:40]=[C:39]1[C:47]1[CH:55]=[CH:54][CH:53]=[C:49]2[CH2:50][CH:51](Br)[C:48]=12.BrCC1C=CC([C:64]2OC3C=CC=CC=3[N:68]=2)=CC=1F>>[Cl:1][C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([CH2:17][C:24]#[N:25])=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[Cl:19][C:20]1[CH:21]=[C:22]([Cl:37])[C:23]2[O:27][C:26]([C:28]3[CH:33]=[CH:32][C:31]([CH2:34][C:39]#[N:40])=[CH:30][CH:29]=3)=[N:25][C:24]=2[CH:36]=1.[O:38]1[C:42]2[CH:43]=[CH:44][CH:45]=[CH:46][C:41]=2[N:40]=[C:39]1[C:47]1[CH:55]=[CH:54][CH:53]=[C:49]2[CH2:50][CH:51]([C:64]#[N:68])[C:48]=12