HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 2-[4-(1-Bromoethyl)-2-fluorophenyl]benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-(4-Ethyl-2-fluorophenyl)-1,3-benzoxazole | HCID 20230225 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 2-[4-(1-Bromoethyl)-2-fluorophenyl]benzoxazole | HCID 21413793 | — |
Reaction Steps
A mixture of 26 gm. 2-(4-ethyl-2-fluorophenyl) benzoxazole, 19.76 gm. of N-bromosuccinimide and 50 mg. of dibenzoyl peroxide in 150 cc. of carbon tetrachloride is refluxed until the N-bromosuccinimide is consumed. The reaction mixture is filtered and the filtrate concentrated to give a 2-[4-(1-bromoethyl)-2-fluorophenyl]benzoxazole, m.p., 103°-104° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046905 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-a2cfb808dff14d75a24ee277bba2af3a |
| Source note | uspto-grants-1977_09 |