HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → 4-(Benzyloxy)-3-chlorobenzohydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 21413907 | HCID 21413907 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(Benzyloxy)-3-chlorobenzohydrazide | HCID 12448961 | 96.7% |
Reaction Steps
Ethyl 4-benzyloxy-3-chlorobenzoate [c.f., Jones & Robinson, J. Chem. Soc. 3845 (1955)] (32.0 g., 0.11 mole), 25 ml. methanol and 20 ml. 95% hydrazine are stirred under reflux for 8 hours and cooled to room temperature. The mixture is filtered and the resulting solid dried in vacuo to give 29.4 g. 4-benzyloxy-3-chlorobenzoic acid hydrazide (96.7% yield), m.p. 168°-171° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046909 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-6e3ebfad739b410591d288427037f990 |
| Source note | uspto-grants-1977_09 |