HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-Methyl-3-{2-[4-(4-toluyl)piperidyl]ethyl}indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-(4-Methylphenyl)piperidine | HCID 544751 | — |
| Reactant | 3-(2-Bromoethyl)-2-methyl-1H-indole | HCID 15323765 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Methyl-3-{2-[4-(4-toluyl)piperidyl]ethyl}indole | HCID 20311722 | — |
Reaction Steps
A solution of 11.8 g of 3-(2-bromoethyl)-2-methylindole, 20.3 g of 4-(4-toluyl)piperidine [Example 5(a)] in 500 ml of dimethylformamide is treated according to the manipulative procedure described in Example 3(b) to give the off-white solid, mp 192°-194° C., 2-methyl-3-{2-[4-(4-toluyl)piperidyl]ethyl}indole from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046900 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-67a14ec686164d6899400e002ef32336 |
| Source note | uspto-grants-1977_09 |