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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2071586Generated: October 31, 2026

Bromine → HCID 70634610, compound

https://huagongshe.com/reaction/2071586

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
ReactantLithium methanolateHCID 4177230—
ReactantHCID 70561563HCID 70561563—
SolventTetrahydrofuranHCID 8028—
ProductHCID 70634610HCID 70634610—

Reaction Steps

In accordance with the procedures described by Example 1, benzhydryl 7-(2-thienylacetamido)-3-methylenecepham-4-carboxylate was reacted with 8 equivalents of lithium methoxide in tetrahydrofuran in the presence of 8 equivalents of bromine at -80° C. to provide the title product:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04048160
Source datasetuspto-grants-1977_09
ORD IDord-af7ebb2f9db947c9a92e379ff22fff36
Source noteuspto-grants-1977_09