HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(1-Butyl)hydrazino-4-chloro-2-methyl-5-nitropyridine-3-carboxylic acid ethyl ester → 5-Amino-6-butylamino-4-chloro-2-methylpyridine-3-carboxylic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(1-Butyl)hydrazino-4-chloro-2-methyl-5-nitropyridine-3-carboxylic acid ethyl ester | HCID 53778077 | — |
| Reactant | 4-Chloro-6-(1-ethyl)hydrazino-2-methyl-5-nitropyridine-3-carboxylic acid, ethyl ester | HCID 86734417 | — |
| Product | 5-Amino-6-butylamino-4-chloro-2-methylpyridine-3-carboxylic acid, ethyl ester | HCID 12387619 | 72% |
Reaction Steps
By replacing 4-chloro-6-(1-ethyl)hydrazino-2-methyl-5-nitropyridine-3-carboxylic acid, ethyl ester in Example 1 c with 6-(1-butyl)hydrazino-4-chloro-2-methyl-5-nitropyridine-3-carboxylic acid ethyl ester, 5-amino-6-butylamino-4-chloro-2-methylpyridine-3-carboxylic acid, ethyl ester is obtained. Yield 72%, b.p. 200°-210°/0.01.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04048182 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-d878edd7d27d47f883aab0f99acaa497 |
| Source note | uspto-grants-1977_09 |