Diphenyl Ether → HCID 178479971, compound

Participants

Reaction Steps

152 g. of 1-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-7-(1H)-one (0.67 mol.) in 500 ml. of diphenyl ether are heated at 250°, while stirring, for 90 minutes. After standing overnight, the crystallized 2-methyl-6-phenyl-2H-pyrazolo[3,4-b]pyridin-4-ol is filtered off, washed with ether and dried at 70°, yield: 146.6 g. (96%); m.p. 241°-243°. A sample recrystallized from acetonitrile melts at 242°-244°.

Provenance & Evidence