HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-(3-Pyrazolyl) propylguanidine hemisulphate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | S-methyl isothiourea hemisulfate | HCID 6604939 | — |
| Reactant | 3-(1H-Pyrazol-3-yl)propan-1-amine | HCID 178510927 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(3-Pyrazolyl) propylguanidine hemisulphate | HCID 178512790 | — |
Reaction Steps
An intimate mixture of 3-(3-aminopropyl)pyrazole (4.7 g) and S-methylthiouronium sulphate (4.9 g) is fused at 140° C for 1 hour. After cooling, methanol is added and the filtered methanol solution is subsequently diluted with ethanol. The solid obtained is recrystallised from methanol-ethanol affording 3-(3-pyrazolyl) propylguanidine hemisulphate, m.p. 210° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04048319 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-81ce1a5d4bc742a08cd2adb7a6a36678 |
| Source note | uspto-grants-1977_09 |