Benzylamine → HCID 21412663, compound

HRID 2071795Notes

Reaction equation

HRID 2071795 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([CH:8]([CH3:12])[C:9]([OH:11])=[O:10])[CH:5]=[CH:4][C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>CCOCC>[OH:1][C:2]1[CH:7]=[C:6]([CH:8]([CH3:12])[C:9]([O-:11])=[O:10])[CH:5]=[CH:4][C:3]=1[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1.[CH2:19]([NH3+:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 20333460HCID 20333460, compound

Product 1

HCID 21412663HCID 21412663, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

2-(2-hydroxy-4-biphenylyl)propionic acid (140 mg.) in ether (5 ml.) was mixed with benzylamine (62 g.) in ether (5 ml.). The precipitate was collected, washed with ether, dried in vacuo and recrystallised for absolute alcohol/ether to give benzylammonium 2-(2-hydroxy-4-biphenylyl)propionate, m.p. 183°-185° C.

Workup

  1. customThe precipitate was collected
  2. washwashed with ether
  3. customdried in vacuo
  4. customrecrystallised for absolute alcohol/ether

Sources & evidence

ORD record
ord-0f58a13887c7488387796fe78dbbf0c1
Source dataset
uspto-grants-1977_09
Patent number
US04048332

Reaction notes

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